Medications to Treat Anxiety Therapy is the most effective treatment for anxiety, sometimes an infrequent course of medication is required. Medications to treat anxiety include antidepressants and tranquilizers. SSRI antidepressants such as citalopram (Celexa), the escitalopram (Lexapro) and sertraline (Zoloft), improve communication between nerve cells in the brain, and may
